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Abstract #3180

The potential of ultra-high resolution 7T T2-weighted TSE to assess the glymphatic system’s structure

Hendrik Mattern1,2 and Oliver Speck1,2,3,4
1Biomedical Magnetic Resonance, Otto von Guericke University, Magdeburg, Germany, 2German Center for Neurodegenerative Disease, Magdeburg, Germany, 3Center for Behavioral Brain Sciences, Magdeburg, Germany, 4Leibniz Institute for Neurobiology, Magdeburg, Germany

Synopsis

Keywords: Data Acquisition, Neurofluids

In this proof-of-principle study the currently untapped potential of UHF MRI is shown. Two young, healthy volunteers were scanned at 7T with 2D 0.25x0.25x1.0mm T2w TSE depicting a substantial number of PVS. At this high resolution, vessel segments inside the PVS could be studied and quantified. Further, hyperintense structures around and inside the dura and sinuses were depicted clearly.

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Keywords