Abstract #3190

Intracranial Hemorrhage Patient CSF Susceptibility Variation: Implications for Quantitative Susceptibility Mapping Reference Selection.

Shutao Wang¹, Pascal Spincemaille², Magdy Selim³, Ajith J Thomas⁴, Aristotelis Filippidis⁵, Yan Wen⁶, Yi Wang², and Salil Soman¹

¹Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States, ²Department of Radiology, Weill Cornell Medicine, New York, NY, United States, ³Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States, ⁴Department of Neurological Surgery, Cooper University Health Care, Cooper Medical School of Rowan University, Camden, NJ, United States, ⁵Neurosurgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States, ⁶GE Healthcare, New York, NY, United States

Synopsis

Keywords: Neurofluids, Quantitative Susceptibility mapping, CSF BloodQSM is an emerging MR technique with many clinical applications, especially in the brain. CSF has been used by many researchers as the reference region to obtain quantitative QSM values for inter-subject comparison. Here, we demonstrate the QSM values at hemorrhagic CSF sites are significantly different from that at non-hemorrhagic CSF sites in the same patient with various types of intracranial hemorrhage. This finding has significant clinical implication as selection of CSF as the reference region should be made with caution in patients with intracranial hemorrhage.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.