Abstract #3209

Imaging Nigrosome-1 using Wave-CAIPI Susceptibility Weighted Imaging at 3T

Peng Liu¹, Naying He¹, Youmin Zhang¹, Caixia FU², Qing Li³, E. Mark Haacke⁴, Yu Liu¹, Wei Liu², Xinhui Wang¹, Daniel Polak⁵, and Fuhua Yan¹

¹Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, ²Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China, ³Siemens Healthineers Ltd., Shanghai, China, ⁴Wayne State University, Detroit, MI, United States, ⁵Siemens Healthcare GmbH, Erlangen, Germany

Synopsis

Keywords: Parkinson's Disease, Data Acquisition, Magnetic resonance imaging, Nigrosome-1, Susceptibility Weighted ImagingIn this work, the ability of Wave-CAIPI accelerated 3D SWI for imaging the Nigrosome-1(N1) sign was evaluated. Short-TE, long-TE and conventional SWI protocols were compared for the detection of the N1 sign. Qualitative and quantitative analyses were used to evaluate the presence or absence of the N1 sign and the contrast-to-noise (CNR) of the N1 sign relative to adjacent tissues. The results showed that Wave-CAIPI SWI had no significant differences with conventional SWI for recognizing the N1 sign. Wave-CAIPI SWI can be a replacement of conventional SWI (4 min 52s) with shorter scan times of 2min 26s covering the whole brain.

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