Abstract #3228

Differentiation of atypical high-grade glioma from primary central nervous system lymphoma with mean apparent propagator-MRI

Eryuan Gao¹, Guohua Zhao¹, Huiting Zhang², Xiaoyue Ma¹, Peipei Wang¹, Jie Bai¹, Xu Yan², Guang Yang³, and Jingliang Cheng¹

¹Department of Magnetic Resonance, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China, ²MR Scientific Marketing, Siemens Healthcare, Shanghai, China, ³Shanghai Key Laboratory of Magnetic Resonance, East China Normal University, Shanghai, China

Synopsis

Keywords: Tumors, Diffusion/other diffusion imaging techniques, mean apparent propagatorAtypical high-grade glioma (HGG) (with no or little necrosis) and primary central nervous system lymphoma (PCNSL) are difficult to distinguish in routine MR images but their treatment strategies are totally different. Therefore, it’s important to distinguish between them before treatment. This study aimed to investigate the diagnostic efficiency of quantitative analysis based on mean apparent propagator-MRI in discriminating atypical HGG from PCNSL. Through quantitative analysis of MAP parameters, we found that MAP-MRI performed well in differentiating between atypical HGG and PCNSL.

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