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Abstract #3234

IMPROVED EX-VIVO IMAGING USING BRAIN & CONTAINER-SPECIFIC 3D-PRINTED HOLDERS

Sethu K. Boopathy Jegathambal1, Ilana Ruth Leppert2, David A. Rudko2, and Amir Shmuel2
1Department of Biomedical Engineering, McGill University, Montreal, QC, Canada, 2McConnell Brain Imaging Center, Montreal Neurological Institute and Hospital, Montreal, QC, Canada

Synopsis

Keywords: Data Acquisition, Ex-Vivo Applications, Brain Ex-Vivo MRIDepending on the medium, it might be difficult to maintain the brain stable during ex-vivo imaging. In addition, the SNR might not be homogeneous. We propose using brain and container-specific 3D-printed models for holding the brain. The method requires preliminary imaging of the container and the brain. Then, a 3D-printed model is created, with profiles that match the surface of the brain on one side and the inner surface of the container on the other. The holder is designed to maintain the brain stable in space, where the SNR is high and homogeneous, while allowing contact with the immersion fluid.

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Keywords