Abstract #3255

Quantitative MRI of DCE andIVIM for differentiating low-risk from non-low-risk early-stage endometrial carcinoma

Hongxia Wang¹, Ruifang Yan¹, Beiran Wang¹, Zhong Li¹, Xingxing Jin¹, Zhenfang Guo², Wangyi Liu¹, Kaiyu Wang³, Jinxia Guo³, and Dongming Han¹

¹Department of MR, the First Affiliated Hospital, Xinxiang Medical University, Weihui, China, ²Department of Neurology, the First Affiliated Hospital, Xinxiang Medical University, Weihui, China, ³MR Research China, GE Healthcare, Beijing, China

Synopsis

Keywords: Pelvis, CancerFinding a noninvasive and effective means for the risk stratification of early-stage EC is of great benefit to patients. This study aim to investigate the value of dynamic contrast-enhanced MRI (DCE-MRI) and intravoxel incoherent motion (IVIM) in differentiating low-risk from non-low-risk early-stage endometrial carcinoma (EC). Results showed that both DCE-MRI and IVIM facilitate the preoperative identification of low-risk and non-low-risk early-stage EC. Compared with each single parameter, the combination of Ktrans, Ve, and f provided better predictive power and may serve as a superior imaging marker.

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