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Abstract #3262

The value of multimodal functional magnetic resonance imaging in differentiating p53abn from p53wt endometrial carcinoma

Xie Zongyuan1, Tian Shifeng1, and Liu Ailian1
1Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian, China

Synopsis

Keywords: Cancer, Uterusp53 genotyping is important for EC lymph node metastasis and prognosis determination.Multimodal MRI techniques APTw, T2 mapping, mDIXON-Quant and DWI are new tools to determine p53 genotyping.Results of this study indicate the APT value and R2* value in the p53abn group were higher than those in the p53wt group, while the ADC value was lower than those in the p53wt group.Therefore, APTw, mDIXON-Quant and DWI techniques can quantitatively identify p53abn and p53wt EC, it provides a new way for preoperative quantitative evaluation of EC molecular typing.

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Keywords