Abstract #3268

Multicenter consistency of quantitative MRI in cervical cancer

Petra J van Houdt¹, Abel Bregman¹, Kari Tanderup², Robert Hudej³, Marko Zaletelj³, Barbara Šegedin^3,4, Eva E Schaake¹, Ellen M Kerkhof⁵, Laura A Velema⁵, Remi A Nout⁶, and Uulke A van der Heide¹

¹Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, Netherlands, ²Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark, ³Radiotherapy, Institute of Oncology Ljubljana, Ljubljana, Slovenia, ⁴Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia, ⁵Radiotherapy, Leiden University Medical Center, Leiden, Netherlands, ⁶Radiotherapy, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, Netherlands

Synopsis

Keywords: Cancer, Quantitative Imaging, cervical cancerThe reproducibility of quantitative MRI parameters in a multicenter setting is not trivial. In this study we evaluated the in-vivo multicenter consistency of quantitative MRI parameters in cervical cancer patients. DWI, T2 mapping and T1 mapping were available from 66 patients from 3 institutes. ADC values were measured consistently across institutes despite differences in acquisition protocols. For T2 and T1 values differences between institutes were observed, which need to be accounted in future evaluation of the quantitative MRI parameters in relation to treatment outcome.

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