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Abstract #3268

Multicenter consistency of quantitative MRI in cervical cancer

Petra J van Houdt1, Abel Bregman1, Kari Tanderup2, Robert Hudej3, Marko Zaletelj3, Barbara Šegedin3,4, Eva E Schaake1, Ellen M Kerkhof5, Laura A Velema5, Remi A Nout6, and Uulke A van der Heide1
1Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, Netherlands, 2Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark, 3Radiotherapy, Institute of Oncology Ljubljana, Ljubljana, Slovenia, 4Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia, 5Radiotherapy, Leiden University Medical Center, Leiden, Netherlands, 6Radiotherapy, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, Netherlands

Synopsis

Keywords: Cancer, Quantitative Imaging, cervical cancerThe reproducibility of quantitative MRI parameters in a multicenter setting is not trivial. In this study we evaluated the in-vivo multicenter consistency of quantitative MRI parameters in cervical cancer patients. DWI, T2 mapping and T1 mapping were available from 66 patients from 3 institutes. ADC values were measured consistently across institutes despite differences in acquisition protocols. For T2 and T1 values differences between institutes were observed, which need to be accounted in future evaluation of the quantitative MRI parameters in relation to treatment outcome.

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