Abstract #3287

Bloch-McConnell Simulation for Arterial Blood Contrast at 3T and 7T: Adiabatic Null Passage vs Binomial Magnetization Transfer Preparation

Shahrokh Abbasi-Rad^1,2,3,4 and David Norris^1,2

¹Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, Netherlands, ²Erwin L. Hahn Institute for Magnetic Resonance Imaging, University Duisburg-Essen, Essen, Germany, ³Department of Radiology, Harvard Medical School, Boston, MA, United States, ⁴Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States

Synopsis

Keywords: fMRI, Magnetization transfer, Arterial Blood ContrastArterial blood contrast (ABC) uses on-resonance binomial pulse for magnetization transfer preparation to saturate the tissue signal and highlights the contribution of arterioles. Previously, using Bloch-McConnel simulations, we showed that Binomial MT contaminates ABC with T2 contrast. We suggested the use of adiabatic null passage to decrease the T2 effect. We performed Bloch-McConnel simulations at 3T and 7T comparing the performance of binomial and ANP pulses. ANP increased the arterial contribution from 32% to 42% at 3T and from 18% to 30% at 7T. This study concludes that ANP reduces the T2-contamination imposed by binomial MT block and improves ABC.

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