Abstract #3290

Amide Proton Transfer-Weighted MRI in Preoperative Assessment of Microvascular Invasion of Hepatocellular Carcinoma: A Preliminary Study

Jingcheng Huang¹, Chengshi Hou¹, Qingqing Wen², Weiqiang Dou², and Xianfu Luo¹

¹Clinical Medical School of Yangzhou University, Northern Jiangsu People’s Hospital, Yangzhou, China, Yangzhou City, China, ²GE Healthcare, MR Research China, Beijing, P.R. China, Beijing City, China

Synopsis

Keywords: Quantitative Imaging, CEST & MT, APTwConventional MRI methods are difficult to reveal histologic and molecular characteristic of HCC. In this study, we aimed to e explore the feasibility of amide proton transfer weighted (APTw) imaging for predicting microvascular invasion (MVI) of hepatocellular carcinoma. Significant difference in APTw values were observed for MVI positive and negative lesions. With these findings, APTw imaging can be considered a potential technique for noninvasive preoperational assessment of MVI in hepatocellular carcinoma.

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