Meeting Banner
Abstract #3311

Network analysis reveals differences in the topology of structural brain networks of young asymptomatic APOE-epsilon4 carriers

Eirini Messaritaki1, Thomas M Lancaster1,2, Katherine E Tansey3, and Derek K Jones1
1Psychology, Cardiff University, Cardiff, United Kingdom, 2Psychology, University of Bath, Bath, United Kingdom, 3Cardiff University, Cardiff, United Kingdom

Synopsis

Keywords: Alzheimer's Disease, Alzheimer's DiseaseThis work explores the link between the topological properties of brain structural networks and APOE-epsilon4 in young asymptomatic adults. We investigated the sensorimotor, visual and default-mode networks. We found evidence that there are differences in the mean clustering coefficient of the sensorimotor network of carriers versus non-carriers, with the left caudal middle frontal, left precentral, right postcentral and right precentral gyri driving the differences. Interestingly, the mean clustering coefficient was higher in carriers compared to non-carriers. In contrast, no differences were found for the visual or the default-mode networks.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords