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Abstract #3347

Brain activity alterations in premature ejaculation patients before and after treatment with sertraline

Shaowei Liu1, Jianhuai Chen2, and Weiqiang Dou3
1Radiology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China, 2Andrology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China, 3GE Healthcare, MR Research China, Beijing, China

Synopsis

Keywords: Brain Connectivity, Brain ConnectivityThis study aimed to explore the central neural mechanisms underlying sertraline in the treatment of premature ejaculation (PE). Resting-state functional magnetic resonance imaging (rs-fMRI) of PE patients before and after treatment with sertraline were acquired. The brain regions with altered regional homogeneity (ReHo) values were found. Increased activity in the occipital lobe and decreased activity in the prefrontal and parietal lobe and thalamus might be the mechanisms of sertraline in the treatment of PE.

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