Keywords: Gray Matter, Aging, Machine Learning, Artificial IntelligenceThe volume of the hippocampus and temporal horn of the lateral ventricle provides insight into the state of neurological health and the changes in volume are associated with conditions such as traumatic brain injury1, Alzheimer's Disease 2 and treatment response. It remains an open question what are the normal age-related changes over time in hippocampal and temporal horn volumes in an average healthy population cohort. We seek to establish these baseline parameters via AI-based MRI brain segmentation and quantification techniques applied to a large cohort of screened healthy patients.
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