Keywords: Gray Matter, Diabetes, Cerebrovascular functionPatients with diabetes mellitus type 1 (T1D) demonstrate brain alterations including gray matter (GM) atrophy. We examined whether a GM reduction could be related to cerebrovascular dysfunction. GM volume was measured by anatomical MRI. Cerebrovascular function was examined by measuring cerebral blood flow, oxygen metabolism and lactate concentration in response to inhalation of hypoxic air using phase-contrast MRI and MRS. T1D patients were evaluated for albuminuria as indication of vessel damages. Patients with T1D and albuminuria had reduced GM compared to patients with normal kidney function or healthy controls, however, the GM atrophy could not be related to cerebrovascular dysfunction.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords