Abstract #3397

Differentiation of Triple-negative and HER2 Positive Breast Cancer Using DISCO CE-MRI

Guo Haodong¹, Dmytro Pylypenko², Li Haige¹, Zhu Jianguo¹, Yuan Xiaofan¹, and Zhang Ziyan¹

¹the Second Affiliated Hospital of Nanjing Medical University, Nanjing, China, ²GE Healthcare, China, Beijing, Beijing, China

Synopsis

Keywords: Quantitative Imaging, Breast, DISCO CE-MR This study aims to investigate the feasibility triple-negative and HER2 positive breast cancer using DISCO CE-MRI. A total of 96 patients were recruited in the study. Quantitative and semi-quantitative parameters were used. k_ep and TTP had diagnostic value for triple-negative breast cancer. The AUC of k_ep and TTP were 0.870 and 0.928. k_ep had diagnostic value for HER2 positive breast cancer.The AUC of k_ep was 0.832. Our findings suggest that DISCO CE-MRI parameters might be reliable quantitative indicators for the differential diagnosis of triple-negative breast cancer and HER2 positive breast cancer.

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