Abstract #3399

Comparing L1 and L2 Regularizations for Quantitative Transport Mapping of Tumor: an Image Quality Analysis

Dominick Romano^1,2, Qihao Zhang^1,2, Ilhami Kovanlikaya², Pascal Spincemaille², and Yi Wang^2,3

¹Biomedical Engineering, Cornell University, New York, NY, United States, ²Radiology, Weill Cornell Medical College, New York, NY, United States, ³Biomedical Engineering, Cornell University, Ithaca, NY, United States

Synopsis

Keywords: Quantitative Imaging, Perfusion, RegularizationThis study compared L1 and L2 regularized Quantitative Transport Mapping (QTM^1-3) of dynamic contrast enhanced (DCE) MRI in breast and neck tumor using image quality scoring. Improved consistent soft tissue and lesion characterization was observed when using the L1 norm.

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