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Abstract #3407

Influence of different confounders on measurements results of 2D Flow MRI Examinations in Healthy Travelling Volunteers

Ralf Felix Trauzeddel1,2, Thomas Grandy3, Elias Daud1,2, Maximilian Müller1,2, Darian Viezzer1,2, Thomas Hadler1,2, Ning Jin4, Daniel Giese5,6, and Jeanette Schulz-Menger1,2,3
1Working Group on Cardiovascular Magnetic Resonance, Experimental and Clinical Research Center, a joint cooperation between the Charité Universitätsmedizin Berlin and the Max-Delbrück-Center for Molecular Medicine, Berlin, Germany, Charité - Universitätsmedizin Berlin, Berlin, Germany, 2Partner Site Berlin, DZHK (German Centre for Cardiovascular Research), Berlin, Germany, 3Department of Cardiology and Nephrology, Helios Hospital Berlin-Buch, Berlin, Germany, 4Cardiovascular MR R&D, Siemens Medical Solutions USA, Inc., Cleveland, Ohio, USA, Cleveland, OH, United States, 5Magnetic Resonance, Siemens Healthcare GmbH, Erlangen, Germany, 6Institute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany, Erlangen, Germany

Synopsis

Keywords: Quantitative Imaging, Heart, 2D FlowVarious confounders can have an influence on the results of cardiovascular MRI (CMR) examinations. Data about systematic investigations of such confounders are sparse. 2D Flow CMR using segmented and realtime measurements was performed in 20 healthy travelling volunteers to examine the influence of beat-to-beat variability between different heart cycles, sequence types, field strengths and scanner configurations as well as examiners on forward flow volume and peak velocity and compared to 95% tolerance intervals established by intraobserver analysis to test for comparability and precision of measurements which revealed good to very good comparability regarding various physiological, technical and post- processing confounders.

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Keywords