Keywords: Artifacts, High-Field MRI, MP2RAGE, 7TMP2RAGE requires denoising of the synthesized T1-weighted image. The conventional denoising method is to add a constant in the synthesis that alters the brain signal. This affects brain segmentation. A new denoising method has been developed to denoise it with preserving the brain signal. The new method estimates the bias field from two inversion images and sets the noise floors at the low and high noise levels in proportion to the bias field. The denoise weight is calculated at each voxel using the two noise floors. The proposed denoising method worked reliably with preserving the brain signal.
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