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Abstract #3459

MRI-based tumor shrinkage patterns after early neoadjuvant therapy in breast cancer: Correlation with subtypes and pathological response

Mengfan Wang1, Siyao Du1, Lizhi Xie2, Min Zhao2, and Lina Zhang1
1The First Hospital of China Medical University, Shenyang, China, 2GE Healthcare, Beijing, China

Synopsis

Keywords: Breast, Cancer, breast cancer, neoadjuvant chemotherapyWe analyzed the correlation between MRI-based tumor shrinkage patterns after the early stage (first and second cycles) of NAC and pathological response in different subtypes. Fragmentation and diffuse decrease are collectively referred to as non-CS. We found that non-CS could be observed in some patients after the early stage of NAC, and non-CS and pCR were significantly correlated in HR+/HER2 subtypes after the first cycle of NAC.

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