Abstract #3462

Feasibility of 3D Quantitative Synthetic MRI for Discriminating Immunohistochemical Status in Invasive Ductal Carcinoma of the Breast

Maki Amano^1,2, Shohei Fujita^1,3, Naoyuki Takei⁴, Katsuhiro Sano¹, Akihiko Wada¹, Kanako Sato¹, Junko Kikuta¹, Yoshiki Kuwatsuru¹, Rina Tachibana^1,5, Towa Sekine^1,5, Yoshiya Horimoto⁶, and Shigeki Aoki¹

¹Radiology, Juntendo University, Tokyo, Japan, ²Radiology, Nihon University Hospital, Tokyo, Japan, ³Radiology, The University of Tokyo Graduate School of Medicine, Tokyo, Japan, ⁴MR Applications and Workflow, GE Healthcare Japan, Tokyo, Japan, ⁵Radiological Sciences, Graduate School of Human Health Sciences, Tokyo Metropolitan University, Tokyo, Japan, ⁶Breast Oncology, Juntendo University, Tokyo, Japan

Synopsis

Keywords: Breast, CancerThe present study aimed to evaluate the feasibility of 3D quantitative synthetic MRI for discriminating the immunohistochemical (IHC) status of invasive ductal carcinoma (IDC) of the breast. We found that volumetric T1 and T2 values of IDC varied according to IHC status, including those for hormone receptors and Ki-67, indicating the feasibility of this method for discriminating the IHC status of IDC of the breast.

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