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Abstract #3466

Assessment of breast lesions using amide proton transfer-weighted imaging and dynamic contrast-enhanced MR imaging: a pilot study

Lulu Zhuang1, Chun Lian1, Zehao Wang1, Ximin Zhang1, Zhigang Wu2, Qingping Gu3, and Rong Huang1
1Department of Radiology, Peking University Shenzhen Hospital, ShenZhen, China, 2Clinical & Technical Support, Philips Healthcare Ltd, ShenZhen, China, 3Clinical Application, Philips Healthcare Ltd, ShenZhen, China

Synopsis

Keywords: Breast, BreastMRI is a non-invasive method for breast lesions diagnosis.However, some imaging features of benign and malignant lesions in breast are still overlap. APT-weighted imaging (APTw) is a endogenous biomarker that allows non-invasive visualization of tissue composition and microscopic information for mobile proteins and peptides. The present study explores the feasibility of the combination of APT and dynamic contrast-enhanced MR imaging to assess of breast lesions. Results of this study indicate the APT value has significant difference between benign and malignant breast lesions.

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Keywords