Abstract #3498

Mood repair in long-term meditators is predicted by rsfMRI functional connectivity of the insula and correlates with FA of the uncinate fasciculus

Quentin Dessain¹, Laurence Dricot², Nicolas Delinte¹, Manon Daussort¹, Benoit Macq¹, Phillipe de Timary², and Ron Kupers²

¹Institute of Information and Communication Technologies, Electronics and Applied Mathematics, Université Catholique de Louvain, Louvain La Neuve, Belgium, ²Institute Of NeuroScience, Université Catholique de Louvain, Bruxelles, Belgium

Synopsis

Keywords: Brain Connectivity, BrainWe used rsfMRI and diffusion imaging to study functional and structural brain changes underlying the psychological trait mood repair in long-term meditators. Results of connectome-based predictive modeling showed that measured “mood repair” scores in meditators could be successfully predicted from rsfMRI data during meditation. The highest degree node in the underlying network was in the anterior ventral insula. Diffusion imaging data further revealed a role of the uncinate fasciculus in the mood repair trait in meditators. The uncinate fasciculus is part of the limbic network, connecting anterior temporal lobe with the inferior prefrontal cortex.

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