Abstract #3501

Risk taking tendency correlate with imbalance functional link between brain networks following 36 hours total sleep deprivation

Jiyuan Li¹, Yunlong Yue¹, Yunlong Song², and Yanfang Jin¹

¹Department of MRI, Beijing Shijitan Hospital, Capital Medical University, Beijing, China, ²Department of CT and MRI, The General Hospital of the Air Force People’s Liberation Army, Beijing, China

Synopsis

Keywords: Brain Connectivity, fMRI (resting state)36 hours sleep deprivation produces a significant deficit in vmPFC functional connectivity and default mode networks (DMN), along with the enhanced functional link between vmPFC and executive control networks (ECN). Furthermore, the negative correlation between vmPFC-DMN and vmPFC-ECN coupling during RW were diminished after TSD. We also find that TSD induced the significantly negative correlation between vmPFC-ECN networks and risk-taking behavior. These results demonstrate that an absence of sleep substantially impaired the balance of large scale brain networks and which in turn predicts risk-taking behavior following 36 hours of TSD.

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