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Abstract #3507

Action execution and observation network: the structural connectome supporting variable force perception

Fulvia Palesi1, Letizia Casiraghi2, Giovanni Savini3, Sonia Paternò1, Egidio D'Angelo1,4, and Claudia AM Gandini Wheeler-Kingshott1,4,5
1Dept. Brain and Behavioural Sciences, University of Pavia, Pavia, Italy, 2Dept. Mental Health and Dependence, ASST of Pavia, Pavia, Italy, 3Dept. Neuroradiology, IRCCS Humanitas Research Hospital, Milan, Italy, 4Brain Connectivity Center, IRCCS Mondino Foundation, Pavia, Italy, 5NMR Research Unit, Department of Neuroinflammation, Queen Square Multiple Sclerosis Centre, UCL Queen Square Institute of Neurology, University College London (UCL), London, United Kingdom

Synopsis

Keywords: Brain Connectivity, Tractography & Fibre Modelling, Action execution observation networkInter-individual interaction is at the basis of social life making it crucial to characterize the functional networks subtending action execution (AE) and action observation (AO). We investigated the integrative properties of previously defined AE and AO functional networks in relation to force perception in terms of their underlying structural brain connectivity. We found that both networks show a strong connectivity between areas involved in sensory/force perception and in motor planning. The cerebellum was engaged both in executing the force-related task and in simulating motor responses, supporting the existence of specific brain networks involving the cerebellum in mirroring and mentalizing mechanisms.

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