Keywords: Gray Matter, Tractography & Fibre ModellingSpherical deconvolution is commonly employed to reconstruct fiber orientations distributions with brain diffusion MRI. A key assumption in spherical deconvolution is that all brain fibers share the same microstructural properties. This is unlikely the case in white matter, but even more so in grey matter. Here, we propose a novel framework to perform spherical deconvolution with fiber specific models. As such, this framework allows to quantify diffusion properties associated to each fiber orientation. In this work, we showcase the application of this framework to investigate the organization of the brain cortex high resolution diffusion MRI data.
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