Keywords: Quantitative Imaging, Quantitative Susceptibility mappingMyelin is a non-neglectable susceptibility source in deep gray matter (DGM) nuclei. Myelination and demyelination processes are essential in DGMs during brain development and aging. However, they have not been investigated by MRI yet. We used a sub-voxel QSM method to independently image and quantify the myelin concentration in brain DGM. We recruited 32 healthy subjects with ages from 4 to 39 years old to describe the DGM myelination and demyelination trajectories. The results suggest that different DGMs display various development trajectories during brain development.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords