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Abstract #3571

Using Compressed Sensing techniques for QSM on multiple sclerosis patients, to what extent can we accelerate?

Émilie Poirion1, Julien Savatovsky1, Jessica Guillaume2, and Mathieu Santin3,4,5
1Imaging department, Rothschild Foundation Hospital, Paris, France, 2Research clinical department, Rothschild Foundation Hospital, Paris, France, 3Institut du Cerveau (ICM) - Paris Brain Institute, Inserm U 1127, CNRS UMR 7225, Sorbonne Université, Paris, France, 4Center for NeuroImaging Research (CENIR), Paris, France, 5MDS Research International, La Rochette, France

Synopsis

Keywords: Quantitative Imaging, Quantitative Susceptibility mappingDespite the characterization of in-vivo biomarkers of MS pathophysiology, there is still a gap between histological knowledges and morphological MRI as it is performed in clinical practice. New MRI advanced techniques, such as quantitative susceptibility mapping (QSM) might help to better describe the disease, but long acquisition times are limiting their uses. Adding acceleration techniques can reduce this time. However, there is no current evidence about their impact on QSM values. Thus, we added four QSM sequences to our clinical protocol of MS follow-up, varying the acceleration factor from classical SENSE (2*2) to high compressed-sense (6, 9, and 12).

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