Abstract #3572

QSM and R2* relaxometry analysis for mapping of white matter hyptension and cognition in patients with lacunar Infarction

HONGWEI LI ¹, XUCHEN YU¹, MIN HE², WEIBO CHEN³, Jing Ding ², and He Wang¹

¹Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China, ²Department of Neurology, The Affiliated Zhongshan Hospital of Fudan University, Shanghai, China, ³Philips Healthcare, Shanghai, China

Synopsis

Keywords: Vessels, PerfusionDue to the lacunar infarcts are small, they are asymptomatic in most cases. However, the location and accumulation of multiple lacunar infarcts might lead to severe physical and cognitive impairment. This lesion, caused by the involvement of cerebral small vessel in the brain, is thought to be associated with an increased risk of Vessel dementia (VaD). Therefore, exploring the perfusion alterations in patients with early lacunar infarction might help with interventions and preventive measures, thereby reducing the social and healthcare burden.

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