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Abstract #3604

Deep-learning auto-segmentation and subtype classification of pituitary adenoma based on MRI radiomics

Bing-Fong Lin1, Dao-Chen Lin2,3,4, and Chia-Feng Lu1
1Department of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan, 2Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan, Taipei, Taiwan, 3Division of Endocrine and Metabolism, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, 4School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan

Synopsis

Keywords: Radiomics, Quantitative Imaging, Pituitary adenomaPituitary adenoma (PA) accounts for approximately 15% in intracranial neoplasms. The classification of PA generally based on the hormone level of blood as the gold standard test, while the analysis of hormone condition using neuroimaging biomarkers was less explored. Accordingly, our study developed a model to automatically segment PA and further used the quantitative and non-invasive MRI technique as image biomarkers to classify the three types of hormone pattern, focusing on corticortroph, gonadotroph, and plurihormonal type. We aimed to provide a feasible classification model based MRI to benefit the clinical management of patients with PA.

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Keywords