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Abstract #3607

Self-navigated high-resolution 3D diffusion MRI using an extended blipped-CAIPI sampling and structured low-rank reconstruction

Ziyu Li1, Xi Chen1, Mark Chiew1,2,3, Karla L. Miller1, and Wenchuan Wu1
1Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom, 2Physical Sciences, Sunnybrook Research Institute, Toronto, ON, Canada, 3Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada

Synopsis

Keywords: Image Reconstruction, Diffusion/other diffusion imaging techniques, Diffusion Acquisition & Reconstruction3D multi-shot multi-slab imaging can provide superior SNR efficiency for high-resolution dMRI but suffers from motion-induced shot-to-shot phase variations. We propose a highly-efficient, self-navigated method to correct for phase variations in 3D multi-slab dMRI. The sampling of each shot is designed to intersect with the kz=0 plane. These intersections are used to reconstruct a 2D phase map for each shot using a structured low-rank reconstruction that leverages the redundancy in shot and coil dimensions. The phase maps are used to eliminate the phase inconsistency in the final 3D multi-shot reconstruction. We demonstrate the method’s efficacy using highly realistic simulations.

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Keywords