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Abstract #3608

Pre-Excitation Gradients for Eddy Current-Nulled Convex Optimized Diffusion Encoding to Mitigate Distortion in 2D Diffusion Weighted Imaging

Matthew J. Middione1, Michael Loecher1, Xiaozhi Cao1, Kawin Setsompop1,2, and Daniel B. Ennis1,3
1Department of Radiology, Stanford University, Stanford, CA, United States, 2Department of Electrical Engineering, Stanford University, Stanford, CA, United States, 3Cardiovascular Institute, Stanford University, Stanford, CA, United States

Synopsis

Keywords: Pulse Sequence Design, Diffusion/other diffusion imaging techniques, Eddy CurrentsDiffusion encoding gradients produce eddy currents that cause image distortions in DWI. Twice refocused spin-echo (TRSE) and eddy current-nulled convex optimized diffusion encoding (ENCODE) mitigate eddy current-induced image distortions in DWI, but at the expense of extending the TE. Herein, we revise the original ENCODE method by playing additional pre-excitation gradient lobes (Pre-ENCODE). Using simulations, phantom experiments, and in vivo imaging we demonstrate that Pre-ENCODE mitigates eddy current-induced image distortions in DWI with a shorter TE than TRSE and ENCODE.

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Keywords