Keywords: Pulse Sequence Design, Diffusion/other diffusion imaging techniques, Eddy CurrentsDiffusion encoding gradients produce eddy currents that cause image distortions in DWI. Twice refocused spin-echo (TRSE) and eddy current-nulled convex optimized diffusion encoding (ENCODE) mitigate eddy current-induced image distortions in DWI, but at the expense of extending the TE. Herein, we revise the original ENCODE method by playing additional pre-excitation gradient lobes (Pre-ENCODE). Using simulations, phantom experiments, and in vivo imaging we demonstrate that Pre-ENCODE mitigates eddy current-induced image distortions in DWI with a shorter TE than TRSE and ENCODE.
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