Keywords: Pulse Sequence Design, Diffusion/other diffusion imaging techniques, Diffusion, Motion compensated diffusion gradients, Reduced FOV imaging, Multi-shot DWIReduced FOV imaging (rFOV) and multi-shot DWI both are very useful techniques to improve spatial resolution for detection of pancreatic lesion. However, respiratory and cardiovascular motion will introduce severe artifacts and ADC bias. Motion compensated diffusion gradients (MOCO) could be used to improve the image quality. In this study, a new sequence named MOCO-rFOV IRIS was developed, which combines the advantages of rFOV, MOCO and image reconstruction using image-space sampling function based multi-shot DWI (IRIS). Results from in vivo data demonstrated that the proposed method could be used to realize motion robust and high resolution DWI for pancreas
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