Abstract #3618

Evaluation of the impact of protocol settings on the variability of model estimations in multicenter diffusion MRI studies

Qiqi Tong¹, Jinsong Li^1,2, Jianhui Zhong^3,4, and Hongjian He^4,5

¹Research Center for Healthcare Data Science, Zhejiang Lab, Hangzhou, China, ²College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou, China, ³Department of Imaging Sciences, University of Rochester, Rochester, NY, United States, ⁴Center for Brain Imaging Science and Technology, College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou, China, ⁵School of physics, Zhejiang University, Hangzhou, China

Synopsis

Keywords: Data Analysis, Diffusion Tensor Imaging, multicenterA multicenter diffusion magnetic resonance imaging (dMRI) study was designed with different b-table schemes, non-diffusion b0 number, and varied echo time (TE) in two 3T scanners of different vendors. Global sensitivity analysis of 6 traveling subjects was conducted to evaluate the impact of imaging protocol setting on the observed cross-scan variability of diffusion metrics.

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