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Abstract #3623

Time-efficient Relaxation-Incorporated IVIM Diffusion Imaging

Kaibao Sun1, Guangyu Dan1,2, Qingfei Luo1, and Xiaohong Joe Zhou1,2,3
1Center for MR Research, University of Illinois at Chicago, Chicago, IL, United States, 2Department of Biomedical Engineering, University of Illinois at Chicago, Chicago, IL, United States, 3Departments of Radiology and Neurosurgery, University of Illinois at Chicago, Chicago, IL, United States

Synopsis

Keywords: Data Acquisition, Diffusion/other diffusion imaging techniquesOverestimation of perfusion volume fraction has been reported in conventional IVIM imaging. In a model known as extended T2-IVIM, compartmentalized relaxation times are incorporated to improve quantification of perfusion volume fraction, which requires acquisition of additional images at different TEs. A main challenge is that the scan time is lengthened, decreasing the efficiency while increasing vulnerability to motion. We herein introduce a novel sequence for time-efficient, relaxation-incorporated (TERI) IVIM imaging to address the aforementioned issues. TERI IVIM imaging uses multiple EPI readouts at different TEs in a single shot. The proposed technique has been demonstrated in the human brain.

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Keywords