Abstract #3630

Morphological and Functional Evaluation of Diabetic Kidney Disease Cohorts by using T2-Weighted and Diffusion Weighted MRI

Kaixuan Zhao^1,2,3, Sheng Li⁴, Zhigang Wu⁵, Thoralf Niendorf⁶, Wenjian Wang⁴, and Zaiyi Liu^1,3

¹Department of Radiology, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences,Guangzhou 510080, China, Guangzhou, China, ²Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China, Guangzhou, China, ³Guangdong Provincial Key Laboratory of Artificial Intelligence in Medical Image Analysis and Application, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China, Guangzhou, China, ⁴Division of Nephrology, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China, Guangzhou, China, ⁵Philips Healthcare Beijing Ltd., Shenzhen, China, ⁶Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrueck Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany, Berlin, Germany

Synopsis

Keywords: Kidney, KidneyDiabetic Kidney Disease (DKD) is the leading cause of end-stage renal disease worldwide. Morphological evaluation of renal compartment volume changes and functional evaluation of renal ADC changes provide comprehensive insight into DKD disease progression. This study compares renal compartment volume changes including: 1) parenchyma volume ,2) pelvis volume, 3) whole kidney volume and 4) parenchyma volume percentage and the functional parameter ADC for DKD groups with different CKD staging. Our results demonstrate that cortical/medullary ADC, parenchyma volume and whole kidney volume are correlated with eGFR and suggest that the cortical ADC is a stronger predictor of eGFR in DKD.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.