Abstract #3632

Improved accuracy of triexponential diffusion analysis of the kidney using motion-corrected reconstruction for free-breathing DWI

Yuki Makino¹, Naoki Ohno², Johannes M Peeters³, Masami Yoneyama⁴, Yu Ueda⁴, Tosiaki Miyati², Yukihiro Matsuura¹, Toshifumi Gabata⁵, and Satoshi Kobayashi^1,2,5

¹Radiology Division, Kanazawa University Hospital, Ishikawa, Japan, ²Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Ishikawa, Japan, ³Philips Healthcare, Best, Netherlands, ⁴Philips Japan, Tokyo, Japan, ⁵Department of Radiology, Kanazawa University Hospital, Ishikawa, Japan

Synopsis

Keywords: Kidney, Diffusion/other diffusion imaging techniquesThe clinical application of triexponential intravoxel incoherent motion analysis in the kidney has been limited because the blurring and misregistration of images caused by respiratory motion during acquisition. To solve this issue, we applied retrospective motion-corrected (MC) reconstruction to free-breathing (FB) DWI of the kidney for accurate triexponential diffusion analysis. Our results showed that triexponential analysis using MC FB-DWI can improve the measurement accuracy and repeatability of triexponential diffusion parameters of the kidney.

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