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Abstract #3635

Renal Cell Carcinoma: Predicting Venous Tumor Thrombus Consistency via IVIM-Diffusion-weighted MR Imaging and Apparent Diffusion Coefficient

Jian Zhao1, Hai-Yi Wang1, Mei-Feng Wang1, Huan-Huan Kang1, Hui-Ping Guo1, Shao-Peng Zhou1, and Hui-Yi Ye1
1Department of Radiology, Chinese PLA General Hospital, Beijing, China

Synopsis

Keywords: Kidney, Diffusion/other diffusion imaging techniquesProblem: Evaluation of VTT consistency through preoperative images has not been reported yet.
Methods: Intravoxel incoherent motion (IVIM)-derived parameters and apparent diffusion coefficient (ADC) were employed to predict VTT consistency of RCC.
Results: Dt of the primary tumor and VTT generated the area under the ROC curve (AUC) values of 0.758 (95%CI: 0.671, 0.832) and 0.712 (95%CI: 0.622, 0.792) for differentiating friable and solid VTT. The AUC value of the model combining Dp and Dt of VTT and Dt of the primary tumor reached 0.886 (95%CI: 0.814, 0.937).
Conclusions: IVIM parameters can effectively predict the VTT consistency of RCC.

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