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Abstract #3637

Correlation of Monopolar ADC and Bipolar ADC measurements to MRE Estimates in Healthy Human Kidney

Gregory McClanahan1,2 and Arunark Kolipaka1,2
1Biomedical Engineering, Ohio State University, Columbus, OH, United States, 2Radiology, Ohio State University, Columbus, OH, United States

Synopsis

Keywords: Kidney, Elastography, MRI, MRE, Diffusion ImagingKidney disease and injury can be assessed using tissue stiffness measurements determined by Magnetic Resonance Elastography (MRE), a method that uses MRI. Similarly, diffusion measurements such as apparent diffusion coefficient (ADC) can also provide useful information regarding tissue health. Our goal is to assess the health of the cortex, medulla, and whole kidney by comparing ADC measurements from monopolar and bipolar diffusion gradient schemes against MRE derived stiffness values. Preliminary results indicate a strong correlation between MRE derived stiffness values and monopolar derived ADC measurements and a fair correlation between MRE derived stiffness values and bipolar derived ADC measurements.

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