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Abstract #3647

In-Plane Balanced Phase-Contrast Steady-State Free Precession (PC-SSFP) for All-in-One Diastolic Function Evaluation

Jie Xiang1, Jerome Lamy2, Maolin Qiu2, and Dana C. Peters1,2
1Department of Biomedical Engineering, Yale University, New Haven, CT, United States, 2Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT, United States

Synopsis

Keywords: Flow, Quantitative ImagingDiastolic function evaluation requires estimates of early and late diastolic mitral valve flow velocities (E and A), and mitral annulus tissue velocity (e’). Our goal was to develop a bSSFP phase-contrast (PC) sequence (PC-SSFP) for in-plane flow-encoding, for simultaneous recording of E and A, and estimation of e’ based on tracking mitral valve motion on cine magnitude images, in a single breath-hold. Phantom and in vivo experiments showed agreement of PC-SSFP with velocities on GRE-based PC providing similar velocity curves, while achieving the high SNR and contrast of bSSFP cine images.

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