Abstract #3661

Validation of real-time phase contrast MRI with online compressed sensing reconstruction in phantom and patients

Tania Lala¹, Lea Christierson^2,3, Petter Frieberg¹, Daniel Giese^4,5, Nina Hakacova ², Pia Sjöberg¹, Ellen Ostenfeld¹, and Johannes Töger¹

¹Clinical Physiology, Department of Clinical Sciences Lund, Skåne University Hospital, Lund University, Lund, Sweden, ²Department of Clinical Sciences Lund, Pediatric Heart Center, Skåne University Hospital, Lund University, Lund, Sweden, ³Department of Biomedical Engineering, Lund University, Lund, Sweden, ⁴Magnetic Resonance, Siemens Healthcare GmbH, Erlangen, Germany, ⁵Institute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany

Synopsis

Keywords: Flow, Velocity & FlowReal-time Phase Contrast MRI with Compressed Sensing reconstruction is a promising method to image cardiac flow in patients with arrhythmia, where cardiac-gated sequences fail. In this study, we compared it against the gated standard clinical flow MRI using a phantom model and in patients. The phantom underwent pulsatile periodic and non-periodic flow. For in vivo validation, non-arrhythmic patient data (N=10) and data from patient with atrial fibrillation (N=1) were collected from the ascending aorta. Non-periodic flow was captured both in the phantom and in vivo. Real-time MRI showed good accuracy in net flow quantification and underestimated peak flow.

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