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Abstract #3669

Combining the benefits of 3D acquisitions and spiral readouts for VASO fMRI at UHF

Alejandro Monreal-Madrigal1, Denizhan Kurban1, Zoia Laraib1,2, Renzo Huber1, Dimo Ivanov1, Nicolas Boulant3, and Benedikt A Poser1
1Maastricht University, Maastricht, Netherlands, 2Polytechnic University of Turin, Turin, Italy, 3University-Paris-Saclay, CEA, CNRS, BAOBAB, NeuroSpin, Gif-sur-Yvette, France

Synopsis

Keywords: fMRI, High-Field MRI, Pulse Sequence DesignVASO fMRI can provide beneficial localization specificity and quantifiability compared to the commonly used BOLD contrast. Previous work has also shown the benefits of using spiral readouts compared to Cartesian EPI. In this work, we employ 3D stack-of-spirals readouts and compare it with the current state of the art 3D EPI readouts for VASO fMRI. The sequence implementation is done using Pulseq, images were reconstructed with MRIReco.jl; functional analysis with an openly available pipeline. We find that a VASO tSNR improvement of a factor of 2 over EPI is achieved using the proposed spiral implementation.

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Keywords