Keywords: fMRI, Contrast Mechanisms, DIANAHere we describe our initial results attempting to observe neuronal activation in humans using the Direct Imaging of Neuronal Activity (DIANA) method. Both visual and auditory paradigms were explored. BOLD and anatomical ROI were tested and dedicated single slice control experiments were performed, but clear DIANA signals remained elusive. The translation of DIANA from animals to humans appears to be non-trivial. Nevertheless, considering the potential payoff continued effort towards this goal may be well worth it. To aid in this quest, parallel studies focused on DIANA’s ability to detect spiking and hyperpolarisation in controlled settings may be of great value.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords