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Abstract #3678

Proprioceptive engagement in the human cerebellum using 7T-fMRI

Emma Brouwer 1,2, Julie Hashimoto 1,3, Nikos Priovoulos1,2, and Wietske van der Zwaag1,2
1Spinoza Centre for Neuroimaging, Amsterdam, Netherlands, 2Computational Cognitive Neuroscience and Neuroimaging, Netherlands Institute for Neuroscience, Amsterdam, Netherlands, 3Vrije Universiteit Amsterdam, Amsterdam, Netherlands

Synopsis

Keywords: fMRI (task based), Brain, cerebellum

The human cerebellum forms an important part of the sensory and motor networks. Specifically, cerebellar damage has been shown to result in difficulty to perform proprioceptive tasks. Hence, studying the functional cerebellar organisation can be of great neuroscientific and clinical interest. This requires high-resolution images due to the thin, highly-foliated cortex of the cerebellum. We investigated the difference between a simultaneous-unilateral-finger-flex (SUFF) and midline-contralateral-finger-touch (MCFT) using B1-shimmed fMRI at 7T. Movements with higher proprioceptive engagement (MCFT) resulted in stronger, more medially located activations on the cerebellar surface compared to movements which are less reliant on proprioception (SUFF).

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