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Abstract #3679

Multi-echo EPI for improving temporal resolution in task-based fMRI at 7T- a dynamic phantom study

Guy Shlomo Baz1,2, Edna Furman-Haran 2,3, and Rita Shmidt1,2
1Department of brain sciences, Weizmann Institute, Rehovot, Israel, 2The Azrieli National Institute for Human Brain Imaging and Research, Weizmann Institute, Rehovot, Israel, 3Life Sciences Core Facilities, Weizmann Institute, Rehovot, Israel

Synopsis

Keywords: fMRI (task based), High-Field MRIUltra-high field MRI provides increased sensitivity, which we aim to utilize for improving the temporal resolution in functional studies. To investigate the achievable resolution at 7T MRI, a dynamic phantom that can generate an fMRI-like time-series was used. A dataset based on block-design with defined time shifts and a range of contrast-to-noise values was used to characterize the effective temporal resolution. Estimated temporal resolution was x1.7 times better for multi-echo compared to single-echo EPI, estimated as 146ms for a scan with TR of 600ms. This study offers a novel approach of optimizing protocols and new insights into fMRI temporal resolution.

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