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Abstract #3695

Implementation of Zoom MRSI at 7T for High-resolution GABA and Glutamate Mapping

Onur Ozyurt1, Diana Rotaru2, Nicholas Farley3, Zoe Kourtzi2, Guy Williams1, and Uzay Emrah Emir3,4
1Wolfson Brain Imaging Center, Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom, 2Department of Psychology, University of Cambridge, Cambridge, United Kingdom, 3School of Health Sciences, Purdue University, West Lafayette, IN, United States, 4Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, United States

Synopsis

Keywords: Spectroscopy, Brain, GABA, Glutamate, MRSIHigh-resolution neurochemical mapping using 2D zoom or reduced field of view (rFOV) magnetic resonance spectroscopy (MRSI) enables the high-resolution metabolic assessment of brain regions that is difficult to probe with standard MRSI sequences. To our knowledge this is the first study to have demonstrated the application of zoom MRSI at 7T for GABA and glutamate mapping.

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