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Abstract #3713

Impact of sampling strategies and residual U-net reconstruction on preserving high spatial frequencies in accelerated low-field MRI

Reina Ayde1,2, Tobias Senft1, Marco Fiorito1, Mauro Spreiter1, Najat Salameh1,2, and Mathieu Sarracanie1,2
1Center for Adaptable MRI Technology (AMT center), Department of Biomedical Engineering, University of Basel, Allschwil, Switzerland, 2AMT center, Institute of Medical Sciences, School of Medicine, Medical Sciences & Nutrition, University of Aberdeen, Aberdeen, United Kingdom

Synopsis

Keywords: Machine Learning/Artificial Intelligence, Image Reconstruction, undersampling, averaging, data samplingLow signal-to-noise (SNR) ratios inherent to low-field (LF) MRI challenge its relevance in clinical applications. Accelerating the acquisition by undersampling k-space followed by reconstruction techniques has already shown promising results. Yet, undersampling is usually done by skipping high-frequency information which can lead to misdiagnosis as small lesions can be missed. In this study, we exploited a specificity of low-SNR regimes, that is signal averaging, to explore different acceleration strategies without skipping crucial information in k-space. The DL-reconstructed images arising from those sampling schemes have been evaluated on acquired in-vivo and ex-vivo LF-MRI datasets, showcasing high-frequency preservation and potential for generalization.

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