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Abstract #3747

Rat angiography from far away: design and performance of a small bath cryostat with NMR capability for transport of hyperpolarized samples.

Andrea Capozzi1,2, Yupeng Zhao3, Magnus Karlsson3, Esben Søvsø Szocska Hansen4, Lotte Bonde Bertelsen4, Christoffer Laustsen4, Mathilde Hauge Lerche3, and Jan Henrik Ardenkjær-Larsen3
1IPHYS, EPFL, Lausanne, Switzerland, 2Health Tech, Technical University of Denamrk, Kgs. Lyngby, Denmark, 3Health Tech, Technical University of Denmark, Kgs. Lyngby, Denmark, 4Aarhus University Hospital, Aarhus, Denmark

Synopsis

Keywords: New Devices, Hyperpolarized MR (Non-Gas), transportable hyperpolarizationHyperpolarization via dissolution Dynamic Nuclear Polarization has the potential to revolutionize diagnostic radiology. Nevertheless, the methodology struggles to enter everyday clinical practice. One of the reasons why broad consensus among clinicians is still missing lies in the technical complexity that characterize hyperpolarization via dDNP. Differently from PET, hyperpolarized MR contrast agent cannot be transported and have to be prepared on-site. We developed a robust methodology to change this paradigm. We herein present our latest updates on transportable hyperpolarization technology.

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