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Abstract #3782

Fast mean kurtosis measurements using navigator-free 3D multi-slab DWI

Chu-Yu Lee1 and Merry Mani1
1Department of Radiology, The University of Iowa, Iowa City, IA, United States

Synopsis

Keywords: Data Acquisition, Diffusion/other diffusion imaging techniques, Kurtosis; Multi-slab; 3D

The fast mean kurtosis measurements using 2D DWI has reduced the scan time substantially but remains subject to low SNR, particularly at b-value = 2500 s/mm2. A larger voxel (≥ 2 mm3) is normally used to increase SNR. This study presents the navigator-free 3D multi-slab DWI for fast mean kurtosis measurements with a resolution of 1.5 mm3. By using a short TR of 2.5 sec, the work demonstrates the promise of using the navigator-free 3D multi-slab DWI for whole-brain fast mean kurtosis measurements with an improved SNR efficiency.

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Keywords