Keywords: Data Processing, Diffusion/other diffusion imaging techniques
Liver fibrosis is one of the leading features in chronic liver disease (CLD) since it conditions the prognosis and guides the treatment strategy. In this work, estimated parameters from various diffusion-weighted MRI models fitted by the Bayesian method were analyzed for the relationship with liver fibrosis through spearman’s correlation and t-test. Four parameters (Ds, σ, D*_F, Dapp) were selected for fibrosis classification and achieved the best result based on the decision tree. Our result suggested that the statistical model and a hybrid IVIM-DKI model are promising models and confirmed the confounding effect of fat for diffusivity to assess liver fibrosis.
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