Keywords: Data Processing, Diffusion Tensor Imaging
A hippocampus-focused, 1 mm isotropic, diffusion tensor imaging 5.5 minutes 3T protocol has yielded high-quality diffusion images and maps. Post-processing with denoising can potentially reduce the scan time considerably. Compared to the previously used 10 direction/10 average protocol, denoising enabled the use of 4 averages for a scan time of only 2.2 minutes to yield acceptable 1 mm isotropic diffusion image quality and mean diffusivity maps (MD) of the whole hippocampus in healthy controls. This rapid protocol was then able to delineate focal and small hippocampal lesions with elevated MD in temporal lobe epilepsy patients.
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